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NEGATIVE PRESSURE WOUND THERAPY VAC MANUAL
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NPWT may also create mechanical forces that influence the wound macroscopically, by drawing the wound edges together, and microscopically, by exerting mechanical forces on tissue that induce cell proliferation, cell migration to the wound, and angiogenesis. This removes molecular factors that inhibit cell growth, improves blood flow to the wound, enhances wound oxygenation, and also improves the flow of nutrients to the wound. NPWT is thought to promote wound healing by providing a warm, moist wound bed while removing wound fluid. Negative pressure wound therapy (NPWT), also referred to as subatmospheric pressure wound therapy or vacuum-assisted wound therapy, involves the application of subatmospheric pressure to the open wound with the goal of creating a controlled, closed wound amenable to surgical closure, grafting, or healing by secondary intention. Although the causes for chronic wounds vary, in all cases, at least one of the phases of wound healing is compromised. Final report published: October 14, 2016Ĭhronic wounds include venous ulcers, diabetic foot ulcers, and pressure sores, with causes that are related to venous insufficiency, pressure, trauma, diabetes, vascular disease, and immobilization.Public comment period: August 19, to September 19, 2016.Final key questions published: May 27, 2016.Public comment period: May 3, to 17, 2016.Draft key questions published: May 2, 2016.
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